Sampling times (h post-dose)
|
0.25, 0.5, 0.75,
1, 1.5, 2, 4, 8, 10, and 24
|
Pre-dose, 0.5, 1, 1.5,
2, 2.5, 3, 3.5, 4,
5, 6, 7, and 8
|
0.083, 1, 2, 3, 4,
5, 6, 7, and 8
|
Abbreviations: LLOQ = lower limit of quantification, homEM = homozygous
extensive metabolisers, hetEM = heterozygous extensive metabolisers, PM
= poor metabolisers |
Abbreviations: LLOQ = lower limit of
quantification, homEM = homozygous extensive metabolisers, hetEM =
heterozygous extensive metabolisers, PM = poor metabolisers |
Abbreviations: LLOQ = lower limit of quantification, homEM = homozygous
extensive metabolisers, hetEM = heterozygous extensive metabolisers, PM
= poor metabolisers |
Abbreviations: LLOQ = lower limit of
quantification, homEM = homozygous extensive metabolisers, hetEM =
heterozygous extensive metabolisers, PM = poor
metabolisers |