SUMO1_HUMAN
|
Small ubiquitin-related modifier 1
|
Cellular processes, such as nuclear transport, transcriptional
regulation, apoptosis, and protein stability
|
101
|
1.587x1077
|
INS_HUMAN
|
Insulin
|
Insulin decreases blood glucose concentration;Diabetes mellitus
|
110
|
4.940x1096
|
SYUA_HUMAN
|
Alpha-synuclein
|
Regulation of dopamine release and transport; Induces fibrillization of
microtubule-associated protein tau; Parkinson disease
|
140
|
2.385x10126
|
TNFA_HUMAN
|
Tumor necrosis factor
|
Induce cell death of certain tumor cell lines; Impairs regulatory
T-cells function; Immune system diseases; Rheumatoid arthritis
|
233
|
3.028x10151
|
PDCD1_MOUSE
|
Programmed cell death protein 1
|
Inhibitory cell surface receptor involved in the regulation of T-cell
function during immunity and tolerance
|
288
|
2.827x10147
|
PDCD1_HUMAN
|
Programmed cell death protein 1
|
Inhibitory cell surface receptor involved in the regulation of T-cell
function during immunity and tolerance
|
288
|
1.762x10155
|
P53_HUMAN
|
Cellular tumor antigen p53
|
A tumor suppressor in many tumor types; induces growth arrest or
apoptos; Cancer.
|
393
|
2.008x10270
|
A4_HUMAN
|
Amyloid-beta A4 protein
|
neurons relevant to neurite growth, neuronal adhesion and axonogenesis;
Alzheimer disease
|
770
|
1.875x10460
|
EGFR_HUMAN
|
Epidermal growth factor receptor
|
Receptor tyrosine kinase binding ligands of the EGF family and
activating several signaling cascades to convert extracellular cues into
appropriate cellular responses; Non-small cell lung cancer
|
1,210
|
5.693x10743
|
INSR_HUMAN
|
Insulin receptor
|
Receptor tyrosine kinase which mediates the pleiotropic actions of
insulin; Diabetes mellitus
|
1,382
|
2.232x10784
|