Statements and Declarations:
Funding: The authors declare that no funds, grants, or other
additional support (except for those indirect funding sources listed in
acknowledgements) were received during the preparation of this research
or manuscript.
Financial disclosures: The authors have no relevant financial
or non-financial interests to disclose.
Author contributions: All authors contributed to the study
conception and design. Material preparation, data collection and
analyses were performed by Huong Meeks, Alison Fraser, and Devin
Etcitty. The first draft of the manuscript was written by Susan Dalton
and all authors commented on subsequent versions of the manuscript. All
authors read and approved the final manuscript.
Ethics approval & Informed consent: Approval was obtained by
the Institutional Review Board at the University of Utah (IRB#
00012636) and the Utah Resource for Genetic and Epidemiologic Research
(UPDB# 00000441) before data collection or analyses were begun. This is
a retrospective observational study of de-identified data and written
informed consent of research participants was waived.