Stillbirth risk among relatives
FDRs, SDRs and TDRs of affected parents had 1.14-fold (95% CI:
1.04-1.26), 1.22-fold (95% CI: 1.11-1.33), and 1.15-fold (95% CI:
1.08-1.21) higher stillbirth odds compared with FDRs, SDRs and TDRs of
unaffected parents, respectively (Figure 2 ). In parental
sex-stratified analyses, FDRs, SDRs and TDRs of affected fathers had
1.17-fold (95% CI: 1.02-1.34), 1.34-fold (95% CI: 1.19-1.51), and
1.14-fold (95% CI: 1.06-1.24) higher stillbirth odds compared with
those of unaffected fathers, respectively (Table 2 ). Similarly,
FDRs, SDRs and TDRs of affected mothers had 1.12-fold (95% CI:
0.98-1.28), 1.09-fold (95% CI: 0.96-1.24), and 1.15-fold (95% CI:
1.06-1.24) higher stillbirth odds compared with those of unaffected
mothers, respectively. Furthermore, stillbirth odds was pronounced among
male relatives, where the corresponding OR (95% CI) for male FDRs, SDRs
and TDRs of affected fathers was 1.22 (1.02-1.47), 1.38 (1.17-1.62), and
1.17 (1.05-1.30), whereas the corresponding OR (95% CI) for male FDRs,
SDRs and TDRs of affected mothers was 1.05 (0.86-1.28), 1.19
(0.99-1.42), and 1.17 (1.05-1.31). Lastly, the OR (95% CI) for female
relatives of affected fathers was 1.10 (0.90-1.35), 1.31 (1.10-1.57),
and 1.12 (1.00-1.25), and the OR (95% CI) for female relatives of
affected mothers was 1.19 (0.98-1.43), 1.01 (0.84-1.21), and 1.12
(1.00-1.25), respectively.