Results
We found 75.7% (56/74) of our participants had an MDRO-positive
culture, with methicillin-resistant Staphylococcus aureus (MRSA,
n=36, 64%) and Pseudomonas aeruginosa (n=8, 14%) being the most
commonly detected organisms. Patients with MDRO-positive cultures had a
greater number of annual non-pulmonary admissions [OR=1.99, 95% CI
(1.21-3.29), P = 0.008], inpatient antibiotic courses
[OR=1.27, 95% CI (1.07-1.50), P =0.006], total antibiotic
courses [OR=1.26, 95% CI (1.08-1.48),P =
0.004], and chronic antibiotic use [OR=2.31, 95% CI (1.12-4.74),P =0.03] compared to MDRO-negative participants. Patients that
acquired MDROs during the study period subsequently required increased
outpatient antibiotics [P = 0.006] but did not have increased
pulmonary admissions or ED visits.