Risk factors for MDRO positivity
We compared MDRO-positive patients clinical risk factors one year prior
to MDRO positivity to clinical risk factors per year of those without a
history of MDRO. One year prior to MDRO positivity those with
MDRO-positive cultures were more likely to have a greater number of
non-pulmonary admissions per year [OR=1.99, 95% CI (1.21-3.29),P =0.008], more inpatient antibiotics use per year [OR=1.27,
95% CI (1.07-1.50), P =0.006], and more IV and oral antibiotic
courses both inpatient and outpatient per year (OR=1.26, 95% CI
(1.08-1.48), P =0.004] compared to MDRO-negative participants
(Table 3). MDRO-positive patients also had significantly more
hospitalizations per year compared to those who are MDRO-negative
[OR=2.01, 95% CI (1.45-2.79) P < 0.001].
MDRO-positive participants were more likely to have received chronic
antibiotics (oral and inhaled) one year prior to MDRO positivity
compared to those without MDRO [OR=2.31, 95% CI (1.12-4.74),P =0.03] (Table 4). Though, no significant effect was found for
type of chronic antibiotics, inhaled versus oral, on MDRO positivity
[OR=1.65, 95% CI (0.30-9.06), P =0.67]. Participants were
divided into two groups those who were never admitted to a transitional
rehab facility and those who have been admitted to transitional rehab
facility. The relationship between those with and without a MDRO and
previous admission to transitional rehab facility was tested and we
found that admission to a transitional rehab facility was not associated
with MDRO positivity [OR=2.33, 95% CI (0.24-22.7), P =0.36].