Statistical analysis
Descriptive and bivariate statistical analyses were used to determine
MDRO incidence and to assess demographic differences between
participants with MDRO-positive cultures and those without a history of
cultured MDRO. To assess risk factors for MDRO positivity we used
univariate mixed logistic regression to compare clinical outcome
variables that occurred one year prior to MDRO acquisition versus those
without MDRO. We used Wilcoxon rank sum test to make a paired comparison
between pre-MDRO and post-MDRO clinical variables. We also used Wilcoxon
rank sum test to assess if having MDRO positivity increases the risk of
complications by comparing clinical outcomes after MDRO-positive
cultures to those without a history of cultured MDRO. In secondary
analysis, we excluded participants with MRSA and reanalyzed our data
using the same statistical tests. Data were analyzed by SASĀ® (SAS
Institute Inc., Cary, NC, USA) 9.4 version. A P -value <
0.05 was considered statistically significant. Missing data were
excluded from the analyses.