Risk factors for MDRO positivity
We compared MDRO-positive patients clinical risk factors one year prior to MDRO positivity to clinical risk factors per year of those without a history of MDRO. One year prior to MDRO positivity those with MDRO-positive cultures were more likely to have a greater number of non-pulmonary admissions per year [OR=1.99, 95% CI (1.21-3.29),P =0.008], more inpatient antibiotics use per year [OR=1.27, 95% CI (1.07-1.50), P =0.006], and more IV and oral antibiotic courses both inpatient and outpatient per year (OR=1.26, 95% CI (1.08-1.48), P =0.004] compared to MDRO-negative participants (Table 3). MDRO-positive patients also had significantly more hospitalizations per year compared to those who are MDRO-negative [OR=2.01, 95% CI (1.45-2.79) P < 0.001]. MDRO-positive participants were more likely to have received chronic antibiotics (oral and inhaled) one year prior to MDRO positivity compared to those without MDRO [OR=2.31, 95% CI (1.12-4.74),P =0.03] (Table 4). Though, no significant effect was found for type of chronic antibiotics, inhaled versus oral, on MDRO positivity [OR=1.65, 95% CI (0.30-9.06), P =0.67]. Participants were divided into two groups those who were never admitted to a transitional rehab facility and those who have been admitted to transitional rehab facility. The relationship between those with and without a MDRO and previous admission to transitional rehab facility was tested and we found that admission to a transitional rehab facility was not associated with MDRO positivity [OR=2.33, 95% CI (0.24-22.7), P =0.36].