Parameters Base model Final model Bootstrap Bootstrap
Estimate (RSE) Estimate (RSE) Median 2.5%-97.5 %
OFV 388.367 371.647 366.768 287.065-459.722
CL (L/h) 3.23 (12%) 1.52 (37%) 1.59 0.74-3.58
V (L) 39.8 (28%) 35.7 (33%) 35.93 11.91-99.40
KA 1.19 1.19
F 0.867 (15%) 0.909 (12%) 0.857 0.639-0.990
θEM 1.42 (14%) 1.45 1.10-1.94
θALB 0.911 (38%) 0.83 0.168-1.527
IIVCL (%) 0.36 (23%) 0.254 (27%) 0.236 0.107-0.424
EPS 0.174 (20%) 0.174 (20%) 0.172 0.108-0.262