2.4 Statistical analysis
The determinations of voriconazole Cmin were analyzed
using multiple linear regression. The univariate analysis was used to
initially screen variables and P <0.1 as the inclusion
criterion. The Pearson or Spearman correlation analysis was used to
analyze the correlation between continuous variables and voriconazole
Cmin. Comparison of voriconazole Cminamong different group were performed by the independent sample t-tests
or the Mann- Whitney U-test. The final results with P<0.05
were regarded as statistically significant. All statistical analyses
performed using SPSS software (version 20.0, SPSS, Inc. Chicago, IL,
USA).