1 |
15 |
Male |
Microinvasive, moderately differentiated adenocarcinoma
arising in a tubulovillous adenoma |
No |
|
|
APC |
|
|
|
|
|
|
|
Alive,
underwent laparoscopic partial
colectomy with removal of sigmoid colon,
undergoing
endoscopic surveillance every 6 months
|
|
|
|
|
|
2 |
15 |
Male |
Moderately differentiated adenocarcinoma invading
through the submucosa |
Yes |
|
|
MSH3 |
|
|
|
|
|
|
|
Alive,
underwent laparoscopic sub-total
colectomy with ileo-sigmoid anastomosis,
undergoing
endoscopic surveillance annually
|
|
|
|
|
|
3 |
15 |
Male |
Poorly differentiated adenocarcinoma with medullary
features and extensive necrosis |
No |
MLH1
c.156del (p.Glu53Argfs*4)
APC
c.3329C>A
(p.Ser1110*)
SMAD4
c.947A>G
(p.Asn316Ser)
|
Alive,
underwent total colectomy with
J-pouch creation and ileoanal anastomosis,
undergoing
endoscopic surveillance annually
|