FIGURE 3 Fingolimod attenuated PCP-induced contextual and tone memory retention deficits in rats in the fear conditioning task . (A) Experimental design of the fear conditioning paradigm. (B) Total percentage of freezing in the contextual fear conditioning test. (C) Total percentage of freezing by the auditory-cued fear conditioning test. Two rats were excluded as explained in the methods section. (Control, n=8; PCP, n=8; PCP+0.5 mg/kg FTY, n=7; PCP+1 mg/kg FTY, n=7). Data were shown as means ± SEM. # P < .05 versus Control, *P < .05 versus PCP. FTY, fingolimod; PCP, phencyclidine; SEM, standard error of the mean.