FIGURE 5 Fingolimod treatment inhibited microglial activation in the dentate gyrus of PCP-treated rats. (A) Confocal microscopic images depict Iba-1 labelled microglia (red), GFAP-labelled astrocytes (green), and DAPI (blue) in the dentate gyrus. Scale bar = 100 μm. Quantitative analysis of Iba-1-positive cells (B) and GFAP-positive cells (C) in the dentate gyrus (n=7 per group). Data were shown as means ± SEM, #P < .05 versus control. FTY, fingolimod; Iba-1, ionized calcium binding adapter molecule 1; GFAP, glial fibrillary acidic protein; PCP, phencyclidine; SEM, standard error of the mean.