Case report :
A 36-year-old male presented to our dermatological department for painful swelling of the sole of the right foot. The lesion started 6 years ago and the patient had no history of trauma. It progressively increased in size and caused a limp when walking. The clinical examination revealed a 5*3 cm single tumor of the right foot, mobile, not painful on palpation with normal overlying skin (Figure 1). The lymph nodes were free. Face and profile radiographs of the foot were normal. The ultrasound showed a circumscribed mass measuring 48*30*26 mm, non-vascularized with heterogeneous tissue that was isoechoic in comparison to the fat tissue. Magnetic resonance imaging demonstrated that it was a multi-lobulated lesion with a fat signal on all sequences. This tumor was located in the extra aponeurotic subcutaneous soft tissue of the sole without deep extension (Figure 2). The Tumor was clinically diagnosed as lipoma. The lesion was excised with the removal of lobulated lipomatous mass weighing 32 g and measuring 5*3*3 cm. It was encapsulated with a well-limited surface. Histological examination of the tumor confirmed a well-circumscribed lipomatous mass composed of proliferating of mature adipocytes arranged in lobules separated by fibrous septa. There were rare places of cellular fibrous spans with spindle cells arranged in bundles. There was no cell atypia, lipoblasts, nor mitotic figures (Figure 3A). Immunohistochemical staining of spindle cells was strongly positive for CD 34, while negative for S-100 protein (Figure 3B). These findings were consistent with the diagnosis of benign Spindle cell lipoma.