Discussion :
We describe an atypical case of Spindle cell lipoma localized on the foot sole. Lipomas of the sole have been rarely reported due to the relative paucity of adipose tissue at this region. Spindle cell lipoma is a rare benign adipose tissue tumor that settles frequently on the back and neck of middle-aged men.1 It is characterized by a slow and asymptomatic course, as in our case. To our knowledge, only 3 cases of Spindle cell lipoma involving the sole of the foot have been reported.2-4 The diagnosis of lipoma was suspected by magnetic resonance imagery, which represents the gold standard investigation of soft tissue tumors of the foot. In addition to histopathological examination, the immunohistochemical examination is necessary for differential diagnosis because of the similarity of Spindle cell lipoma and many benign and malignant soft tissue tumors. It has to be differentiated from cellular angiolipoma, myofibroblastoma, solitary fibrous tumor and mainly spindle cell liposarcoma. Spindle cell lipoma is characteristically composed of a mixture of mature adipocytes and bland spindle cells without significant variation in adipocyte size and shape nor atypical stroma cells.5
Rare lipoblasts maybe showed but are never a prominent finding. CD 34 was positively expressed in this tumor. Our results also confirmed these reports. Surgical excision remains the only treatment.
Authorship: All authors had access to the data and a role in writing this manuscript.