Discussion :
We describe an atypical case of Spindle cell lipoma localized on the
foot sole. Lipomas of the sole have been rarely reported due to the
relative paucity of adipose tissue at this region. Spindle cell lipoma
is a rare benign adipose tissue tumor that settles frequently on the
back and neck of middle-aged men.1 It is characterized
by a slow and asymptomatic course, as in our case. To our knowledge,
only 3 cases of Spindle cell lipoma involving the sole of the foot have
been reported.2-4 The diagnosis of lipoma was
suspected by magnetic resonance imagery, which represents the gold
standard investigation of soft tissue tumors of the foot. In addition to
histopathological examination, the immunohistochemical examination is
necessary for differential diagnosis because of the similarity of
Spindle cell lipoma and many benign and malignant soft tissue tumors. It
has to be differentiated from cellular angiolipoma, myofibroblastoma,
solitary fibrous tumor and mainly spindle cell liposarcoma. Spindle cell
lipoma is characteristically composed of a mixture of mature adipocytes
and bland spindle cells without significant variation in adipocyte size
and shape nor atypical stroma cells.5
Rare lipoblasts maybe showed but are never a prominent finding. CD 34
was positively expressed in this tumor. Our results also confirmed these
reports. Surgical excision remains the only treatment.
Authorship: All authors had access to the data and a role in
writing this manuscript.