What is already known about this subject
- Lean body mass (LBM) correlates better with drug clearance of
doxorubicin, epirubicin and fluorouracil when compared to body surface
area (BSA);
- Patients with comparable BSA values show a wide variety in liver
volume and LBM, while liver volume is strongly correlated with LBM;
- Docetaxel is mainly metabolized by the liver.