Pharmacological studies

Interesting hypothesis, "Allopregnanolone: The missing link to explain the effects of stress on tic exacerbation?" \citep{34423500}.
Report on valbenazine development \citep{33682568}.

Clinical and neuropsychological studies

"Inhibitory Control in Youth with Tourette's Disorder, Attention-Deficit/Hyperactivity Disorder and their Combination and Predictors of Objective Tic Suppressibility" \citep{34411767}.
Procedural memories in TS \citep{34475817}.

Other

 

Treatment

Psychological interventions

A group therapy study compared CBIT to a control condition with education about tics \citep{33415472}. Group CBIT better reduced tics, especially at 3 months after the intervention. Children with behavioral problems had less improvement, whereas higher intellectual functioning portended better results. This report adds to previous suggestions that group therapy—which can reach more patients at lower cost—is an effective way to deliver CBIT.
Homework compliance predicts CBIT treatment success \citep{33770556}.
Mechanisms Underlying Behavior Therapy for Tourette’s Disorder https://link.springer.com/article/10.1007/s40474-021-00225-1
(include?) A pilot study of online mindfulness-based group therapy for adults with tic disorders showed that it was feasible, but with lower adherence to prescribed homework than expected, and only 2 of 5 showed any meaningful improvement \citep{33757602}.
"Long-term Outcomes of Behavior Therapy for Youth With Tourette Disorder" \citep{34508805} [check to see if preprint in 2020 Highlights paper].

Medication

https://www.neurologyadvisor.com/conference-highlights/mds-2021/ecopipam-shows-promise-in-tic-reduction-in-children-with-tourette-syndrome/
Disappointing results from deutetrabenazine study in children and adolescents \citep{34609495}.

Neurosurgery

A collaborative study across several sites revealed several brain regions whose activity, based on fMRI functional connectivity in a healthy population, predicted success of DBS for OCD (10.1016/j.biopsych.2021.04.006). 
Thalamic DBS https://www.mdlinx.com/journal-summary/thalamic-deep-brain-stimulation-for-tourette-syndrome-a-naturalistic-trial-with-brief-randomized/35OXgvYZMOeHEfUvHr1u3s