Introduction:
Extramedullary plasmacytomas are localized plasma cell tumors that arise in tissues outside of the bone marrow which appear to be biologically distinct from solitary plasmacytoma of bone and plasma cell myeloma. Extramedullary plasmacytoma constitutes less than 5% of plasma cell neoplasms.[1,2]Extramedullary plasmacytoma is localized to the upper respiratory tract (nasal cavity and sinuses, nasopharynx and larynx) in over 80% of cases.[3]
In the sinonasal region, the clinical presentation includes nasal obstruction (29.8%), epistaxis, facial swelling, pain, rhinorrhea cranial nerve palsy, and visual loss .cervical lymphadenopathy presented in 5-20%of cases. [4]
According to the radiosensitivity of these tumors, radiotherapy remains the treatment modality of choice. Besides, surgery is suggested to obtain tissue for diagnosis, small localized lesions, and residual disease. [3]
In this report, we describe a 62-year-old female with solitary extramedullary plasmacytoma arising from the right sphenoid sinus to highlight clinical and histological features.