Introduction:
Extramedullary plasmacytomas are localized plasma cell tumors that arise
in tissues outside of the bone marrow which appear to be biologically
distinct from solitary plasmacytoma of bone and plasma cell myeloma.
Extramedullary plasmacytoma constitutes less than 5% of plasma cell
neoplasms.[1,2]Extramedullary plasmacytoma is localized to the upper
respiratory tract (nasal cavity and sinuses, nasopharynx and larynx) in
over 80% of cases.[3]
In the sinonasal region, the clinical presentation includes nasal
obstruction (29.8%), epistaxis, facial swelling, pain, rhinorrhea
cranial nerve palsy, and visual loss .cervical lymphadenopathy presented
in 5-20%of cases. [4]
According to the radiosensitivity of these tumors, radiotherapy remains
the treatment modality of choice. Besides, surgery is suggested to
obtain tissue for diagnosis, small localized lesions, and residual
disease. [3]
In this report, we describe a 62-year-old female with solitary
extramedullary plasmacytoma arising from the right sphenoid sinus to
highlight clinical and histological features.