Conclusion :
Multiple nodules and air space cyst on chest imaging could be a presentation of many deseases such as histiocytosis, TB, fungal infections, sarcoidosis, and occupational lung disease. It can also be a manifestation of hematogenous metastasis to the lungs from thyroid and renal cancers, sarcomas. Adenocarcinoma of the lung, although rarely presenting as multiple nodules or cysts can lead to a delay in diagnosis. We conclude that adenocarcinoma of the lung may be considered a rare but sinister differential diagnosis of multiple nodules and air space cysts on chest imaging. It has a favorable response to tyrosine kinase inhibitorbased therapy even with brain metastasis.
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