Demographics |
Demographics |
Demographics |
Demographics |
Patients |
52 |
103 |
N/A |
Female gender |
27 (51.9) |
50 (48.5) |
0.82 |
Median age of symptom onset in years (IQR) |
9.5 (4.8, 13.0) |
5.0 (2.0,
10.0) |
N/A |
Mean age of symptom onset (SD) |
9.0 (4.4) |
6.1 (4.5) |
<10-3
|
Diagnostic Testing |
Diagnostic Testing |
Diagnostic Testing |
Diagnostic Testing |
Ice cube test |
52 (100.0) |
N/A |
N/A |
Positive ice cube test |
47 (90.4) |
N/A |
N/A |
Negative ice cube test/Atypical cold urticaria
|
5 (9.6)
|
N/A
|
N/A
|
Triggers |
Triggers |
Triggers |
Triggers |
Swimming |
28 (73.7), N=38 |
N/A |
N/A |
Weather/Air |
25 (65.8), N=38 |
N/A |
N/A |
Food |
7 (18.4), N=38 |
N/A |
N/A |
Comorbidities |
Comorbidities |
Comorbidities |
Comorbidities |
Other type of chronic urticaria |
25 (48.1) |
N/A |
N/A |
Chronic spontaneous urticaria |
20 (42.3) |
N/A |
N/A |
Cholinergic urticaria |
3 (5.8) |
N/A |
N/A |
Cholinergic and chronic spontaneous urticaria
|
2 (3.8)
|
N/A
|
N/A
|
Solar urticaria |
0 (0.0) |
N/A |
N/A |
Delayed pressure urticaria |
0 (0.0) |
N/A |
N/A |
Asthma |
16 (30.8) |
15 (14.6) |
0.030 |
Atopic dermatitis |
16 (30.8) |
13 (12.6) |
0.012 |
Allergic rhinitis |
11 (21.2) |
9 (8.7) |
0.054 |
Food allergies |
5 (9.6) |
6 (5.8) |
0.59 |
Autoimmune disease |
2 (3.8) |
6 (5.8) |
0.89 |
Celiac disease |
1 (1.9) |
0 (0.0) |
0.73 |
Type I diabetes mellitus |
1 (1.9) |
2 (1.9) |
1.0 |
IgA nephropathy |
0 (0.0) |
1 (0.97) |
1.0 |
Autoimmune thyroid disease |
0 (0.0) |
2 (1.9) |
0.80 |
Lupus |
0 (0.0) |
1 (0.97) |
1.0 |
Insect venom allergies |
1 (1.9) |
3 (2.9) |
1.0 |
Autoinflammatory disease |
0 (0.0) |
N/C |
N/A |
Family History |
Family History |
Family
History |
Family History |
Atopy |
8 (15.4) |
22 (21.3) |
0.50 |
Chronic urticaria |
9 (17.3) |
12 (11.7) |
0.80 |
Cold urticaria |
3 (5.8) |
N/C |
N/A |
Symptoms |
Symptoms |
Symptoms |
Symptoms |
Angioedema |
15 (28.8) |
24 (23.3) |
0.58 |
Cold-induced anaphylaxis |
9 (17.3) |
N/A |
N/A |
Laboratory Values |
Laboratory Values |
Laboratory Values |
Laboratory Values |
Tryptase (>13.5ug/mL) |
1 (2.3), N=43 |
0 (0.0), N=96 |
0.68 |
IgE ( >240IU/mL) |
25 (64.1), N=39 |
34 (37.8), N=90 |
0.010 |
CRP (>5mg/L) |
2 (4.8), N=42 |
8 (8.7), N=92 |
0.65 |
Blood eosinophils (>0.60 x 109/L) |
7
(15.6), N=45 |
6 (6.0), N=100 |
0.12 |