ColdU Demographics Compared to CSU (Table 1)
We extracted data on a total of 103 pediatric CSU patients from the Netchiporouk et al. study10. Median age of disease onset was 5.0 years (IQR: 2.0, 10.0) and approximately half (48.5%) of CSU patients were female. There was a significantly higher proportion of coldU patients with comorbid asthma (P=0.030), atopic dermatitis (P=0.012), and elevated IgE levels (P=0.010) compared to CSU patients. Mean age of onset was significantly higher in coldU patients (P<10-3). No significant differences were identified in other demographics, comorbidities, or laboratory values.