3.5 Interventions in patients who initiated combined therapy
during versus prior to hospitalization
A combined antithrombotic therapy was initiated during hospitalization
in 360 patients (78% of 460 included patients) while 100 patients
entered the hospital already using a combination of antithrombotics
(22% of 460 included patients).
Out of the 360 patients for whom the combined antithrombotic therapy was
initiated during the hospitalisation, 198 (55%) required at least one
ASP intervention and a total of 251 interventions were carried out.
Out of the total of 100 patients who entered the hospital already using
a combination of antithrombotic therapy 53 (53%) required at least one
ASP intervention and 59 interventions were carried out in total.
In figure 2 the reason of intervention per subgroup is depicted. the
intervention to discontinue antithrombotic therapy due to a lack of
indication was more seen in patients who initiated combined therapy
prior to hospitalization compared to those who initiated during
hospitalization (17.5% versus 27.1%, p = 0.09). This result was
non-significant. In addition, although not statistically significant,
the intervention to define the maximum duration of therapy was more
frequently observed in patients whose combined therapy was initiated
during current hospitalization compared to the group who initiated
therapy prior to hospitalization (67.3% vs 57.6%, p= 0.16).