2.3 Outcomes and follow-up
The primary end-point was all-cause mortality, including cardiac death and non-cardiac death [3]. The secondary endpoint was major adverse cardiac events ( MACE). MACE defined as all-cause mortality, the development of symptomatic congestive heart failure, admission for heart failure, fatal arrhythmia (ventricular tachycardia (VT) and ventricular fibrillation (VF)) and the composite of cardiac death from heart failure, malignant arrhythmia, and SCD [2]. A medical recorder with no information regarding a given patient’s laboratory findings or treatment reviewed all MACE. The endpoint for follow-up was the date of first MACE incidence and was determined through hospital medical records. Telephone interviews and other approaches were used to follow discharged patients through November 30, 2020.