3.1 Search strategy
A systematic literature review and subsequent meta-analysis were performed according to preferred reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Guidelines 20 . We systematically searched in PubMed, EMBASE, and Medline for inherent studies published starting from August 2021. In our meta-analysis, we included randomized clinical trials only. Keywords used to find the desired articles were the following: (1) statin; (2) postoperative atrial fibrillation; (3) statin and atrial fibrillation; (4) statin and postoperative atrial fibrillation. The search only included original studies on human subjects published in the English language. To include pertinent papers, two authors independently searched for additional citations from the reference list of included relevant articles.