Angioedema activity score
The details of the AAS7 questionnaire are shown in Table 2. We found significant differences in angioedema severity between the CHA and CSU-AE patients. The AAS7 score was significantly higher in CSU-AE (median, IQR: 1, [0–1]) than in CHA (median, IQR: 0, [0–1], p= 0.022).
In CHA, 58.1% of patients reported no AE episodes within the previous 7 days, 32.3% had low scores, 9.7% had moderate scores, and no patients had high scores. In CSU-AE, 42.3% of patients had no AE episodes in the past 7 days, 38.5% reported low scores, 11.5% had moderate scores and 7.7% had high scores. Only the CSU-AE patients had severe angioedema episodes in the AAS7 questionnaire (severe AAS7 range: 19–105) (p= 0.041).