Conclusion
After several months passing from the dreadful surges of SARS-CoV-2 infection, many manifestations of long COVID are still evident in the survivors. Moreover, the COVID vaccination has also brought about many adverse events, leading to vaccination hesitancy. POTS has been among the vast range of SARS-CoV-2 infection- and SARS-CoV-2 vaccination-induced complications, which should be considered incompatible settings. Clinicians should be aware of the manifestations and seek the criteria to diagnose and subsequently treat the condition. Moreover, they should advise the patients to receive vaccines despite the probability of adverse events like POTS, since its incidence is quite low after vaccination and the benefits outweigh the potential harms.