INTRODUCTION
Renal Cell Carcinoma (RCC) accounts for 3% of all adult cancers and
85% of all kidney tumors making it the most common renal malignancy
[1]. With an incidence rate of 14.5 per 100,000, RCC is the seventh
most common solid cancer and comprises 3-5% of all adult
malignancies[1, 2]. It has a high recurrence rate of 93% in the
first five years after nephrectomy[3]. Lungs are the most common
site for distant metastasis (50-60%). The median time to recurrence is
15-18 months after nephrectomy. Eighty-five percent of the relapse cases
occur within 3 years of nephrectomy[4].
Here we report a rare case of RCC that presented with lung metastasis 16
years after nephrectomy. Based on our literature review, we found only
ten reported cases with intervals longer than in our case between
nephrectomy for RCC and lung metastasis: 17 years [5], 19
years[6], six cases with 20-28 years intervals [7], 31
years[8], and 37 years[9].