Figure legends
Fig 1 A show the proportion of CD59-negative granulocytes and
erythroid cells detected by flow cytometry; 1B shows FLAER detection in
the peripheral blood of PNH patients by flow cytometry.
Fig 2 The trend of Hb, RET%, LDH and TBIL level changes in 0
to 8 weeks before and after chemotherapy. A1/A2 and B1/B2 show the
average levels of Hb and reticulocyte percentages before and after
chemotherapy from baseline (0 weeks) to 8 weeks after chemotherapy,
respectively. Hb and RET% increased significantly from before
chemotherapy to 8 weeks after chemotherapy. C1/C2 and D1/D2 show the
average levels of LDH and TBIL before and after chemotherapy from
baseline (0 weeks) to 8 weeks after chemotherapy, reflecting the degree
of intravascular hemolysis. After chemotherapy, lactate dehydrogenase
(LDH) levels in all PNH patients decreased to slightly higher than the
upper limit of the normal range in 8 weeks, and the LDH level in 15
patients dropped to the normal range.
Fig 3 Survival rate in the cohort of PNH patients. The overall
survival (OS, %) of all enrolled patients over 10 years is shown inA . There was no significant difference in the effects of age,
Hb level and LDH elevation on survival (B, C, and D).