Figure 2. Clustering heatmap representing the clinical manifestation of genetically confirmed MPS patients.
Figure 3. MPS patients’ ethnicity and age demographics. A) Number of MPS patients among different ethnicities of the Iranian population and relative distribution of MPS types among them. B) Distribution of MPS patients based on their age at diagnosis divided by each MPS type.
Figure 4. Geographical distribution of pathogenic variants associated with MPS IV. Total number of patients = 90. Geographical distribution was determined based on the parental origin of the affected individuals. Variants with a concentrated pattern of distribution in a region are shown underneath.
Figure 5. Geographical distribution of pathogenic variants in the Iranian cohort associated with MPS I. Total number of patients = 59. Geographical origin was determined based on the parental origin of the affected individuals. Variants with a concentrated pattern of distribution in a region are shown underneath.
Figure 6. Geographical distribution of pathogenic variants in the Iranian cohort associated with MPS VI. Total number of patients = 59. Geographical distribution was determined based on the parental origin of the affected individuals. Variants with a concentrated pattern of distribution in a region are shown underneath.
Figure 7. Geographical distribution of pathogenic variants in the Iranian cohort associated with MPS II and III. Total number of MPS II patients = 18. Total number of MPS III patients = 33. Geographical origin was determined based on the parental origin of the affected individuals.