Number |
1687 |
345 |
|
Recipient age at LT, median (IQR), months |
8.00 [6.00, 17.00] |
9.00 [6.00, 17.00] |
0.163 |
Recipient sex, Female |
917 (54.4) |
174 (50.4) |
0.203 |
Recipient weight at LT, median (IQR), kg |
7.70 [6.50, 10.00] |
7.80
[6.90, 10.00] |
0.206 |
Growth retardation |
1067 (63.2) |
225 (65.2) |
0.528 |
Recipient CYP type |
|
|
<0.001 |
AA
AG
GG
|
108 (6.4)
555 (32.9)
1024 (60.7)
|
71 (20.6)
181 (52.5)
93 (27.0)
|
|
Primary disease at transplantation |
|
|
0.325 |
Acute liver failure |
8 (0.5) |
5 (1.4) |
|
Cholestatic liver disease |
1502 (89.0) |
299 (86.7) |
|
Metabolic liver disease |
124 (7.4) |
30 (8.7) |
|
Neoplastic disease |
24 (1.4) |
4 (1.2) |
|
Re-transplantation |
20 (1.2) |
4 (1.2) |
|
Vascular disease |
9 (0.5) |
3 (0.9) |
|
Complications before transplantation |
|
|
|
History of heart disease |
221 (13.1) |
43 (12.5) |
0.816 |
Portal hypertension |
732 (43.4) |
136 (39.4) |
0.194 |
Gastrointestinal bleeding |
258 (15.3) |
57 (16.5) |
0.622 |
Cholangitis |
590 (35.0) |
99 (28.7) |
0.029 |
Ascites |
1057 (62.7) |
225 (65.2) |
0.402 |
GRWR, median (IQR) |
3.14 [2.50, 3.83] |
3.28 [2.57, 3.93] |
0.065 |
Spleen long diameter (IQR),
millimeter |
90.00 [76.00, 107.00] |
93.00 [80.00, 105.00] |
0.144 |
INR, median (IQR) |
1.30 [1.10, 1.67] |
1.29 [1.12, 1.62] |
0.911 |
Albumin, median (IQR), g/dL |
3.49 [3.10, 3.92] |
3.43 [3.05,
3.84] |
0.044 |
TB, median (IQR) |
12.90 [3.50, 20.30] |
12.60 [3.30, 19.20] |
0.663 |
PT, median (IQR) |
14.70 [12.50, 19.00] |
14.60 [12.70, 18.50] |
0.901 |
Child pugh score at transplantation, median (IQR) |
9.00 [7.00,
10.00] |
9.00 [7.00, 10.00] |
0.575 |
PELD score, median (IQR) |
18.00 [11.00, 27.00] |
19.00 [12.00,
26.00] |
0.675 |
Surgical type |
|
|
0.018 |
SLT |
86 (5.1) |
14 (4.1) |
|
OLT |
213 (12.6) |
63 (18.3) |
|
LDLT |
1388 (82.3) |
268 (77.7) |
|
Graft volume reduction |
81 (4.8) |
5 (1.4) |
0.008 |
IS drugs |
|
|
<0.001 |
TAC |
1679 (99.5) |
71 (20.6) |
|
CsA |
8 (0.5) |
274 (79.4) |
|
Addition of MMF |
994 (58.9) |
293 (84.9) |
<0.001 |
Donor CYP type |
|
|
<0.001 |
AA |
217 (12.9) |
83 (24.1) |
|
AG |
699 (41.4) |
198 (57.4) |
|
GG |
771 (45.7) |
64 (18.6) |
|
Donor sex (Female) |
917 (54.4) |
174 (50.4) |
0.203 |
Donor age at LT, median (IQR), years |
29.00 [25.00, 34.00] |
28.00
[23.00, 33.00] |
0.021 |
Donor BMI, median (IQR) |
21.90 [19.40, 24.20] |
21.20 [18.90,
24.10] |
0.06 |