e. Implementation
During the intra-operative period once the sternotomy was performed, the
administration of the drugs was divided in two groups, E group and DEX
group which aim to maintain heart rate at 50-60 (bpm). Coronary
arteriotomy is performed, in the area previously chosen and assessed by
the Cardiothoracic surgeon, a clip of coronary artery retraction is
placed and the anastomosis was made.
Methods of hemodynamic monitoring. During the perioperative
period all patients were monitored with FloTrac/Vigileoï›› a widely
used method that uses CVP and vascular tone to calculate stroke volume
and CO; we compared heart rate and MAP in both groups (ESM and DEX) at
the following times:
- t1 = baseline,
- t2 = time of sternotomy,
- t3 = time of coronary anastomosis,
- t4 = time of sternal closure,
The graft was obtained from the internal mammary artery. The mediastinum
and pleural cavities were drained intraoperatively, and the sternum
closed. Both ESM and DEX infusions were suspended, once the placement of
the sternal closure was completed, each patient was then transferred to
the ICU.