Declaration of Competing Interest
C.D., R.T., A.M.D, S.Y.G, J.M.C., and C.D.E have nothing to disclose
M.J.H. received honoraria from Amgen GmbH, Baxter Deutschland GmbH, Biotest Pharma GmbH, CSL-Behring GmbH, Fresenius Kabi GmbH, Leo Pharma GmbH, Merck-Serono GmbH, Novartis Pharma GmbH, Pfizer PFE GmbH, Roche AG, Sun Pharmaceuticals
L.N. reports grants from German Center for Lung Research, during the conduct of the study; personal fees from Vertex Pharmaceuticals, personal fees from Boehringer Ingelheim, outside the submitted work; .
M.S. is a central multiple-breath washout overreader in the Vertex sponsored trial VX16-809-121 and principal investigator and subinvestigator in a number of Vertex sponsored trials on CFTR modulators in patients with CF
B.T. reports grants from German Federal Ministry of Education and Research , during the conduct of the study; personal fees and other from Vertex Pharmaceuticals, outside the submitted work;
M.A.M. reports grants from German Federal Ministry of Education and Research , grants from Einstein Foundation Berlin, during the conduct of the study; personal fees and other from Boehringer Ingelheim, personal fees from Arrowhead Pharmaceuticals, personal fees and other from Vertex Pharmaceuticals, personal fees from Santhera, personal fees from Sterna Biologicals, personal fees from Enterprise Therapeutics, personal fees from Antabio, personal fees from Kither Biotech, personal fees from Prieris Pharmaceuticals, outside the submitted work;