5 | CONCLUSIONS
Roundworms has undergone significant differentiation and host
specificity in the process of accompanying host evolution. This can be
clearly seen in the evidence in morphology and molecular biology. The
roundworm genome provides the possibility to study the details of gene
selection or loss in the process of roundworm differentiation. It is
also the case that some of the genes we have identified have potentially
allowed new avenues for gene selection and intestinal environment
adaption, for example, epidermal chitin synthesis, environmental
information and essential amino acid metabolism. In addition, population
genomics analysis and drug prediction provide insights for revealing the
impact of deworming history on population genetic structure and
prevention.