5 | CONCLUSIONS
Roundworms has undergone a remarkable evolutionary adaptation to
specific hosts accompanying host evolution. The roundworm genome
provides a possibility to study the details of gene selection or loss in
the process of evolution and adaptation to the intestinal environment,
including genes involved in epidermal chitin synthesis, environmental
information, and essential amino acid metabolism. In addition,
population genomics analysis and drug prediction provide insights
revealing the impact of deworming history on population genetic
structure and future development of novel anthelmintic drugs.