Chromosome-scale
assembly and whole-genome sequencing of 266 giant panda roundworms
provide insights into their evolution, adaptation and potential drug
targets
Lei Han1,5†,
Tianming Lan2,3†, Desheng Li4†,
Haimeng Li2,7, Linhua Deng4, Zhiwei
Peng1, Shaowen He15, Yanqiang
Zhou1, Ruobing Han1, Lingling
Li1, Yaxian Lu1, Haorong
Lu8,9, Qing Wang12, Shangchen
Yang10, Yixin Zhu12, Yunting
Huang8,9, Xiaofang Cheng11, Jieyao
Yu8,9, Yulong Wang1, Heting
Sun13, Hongliang Chai1, Huanming
Yang2, Xun Xu2,8, Michael
Lisby3, Quan Liu1,6*, Karsten
Kristiansen3,14*, Huan Liu2,3*,
Zhijun Hou1,5*
1College of Wildlife and Protected Area, Northeast
Forestry University, Harbin 150040, China
2State Key Laboratory of Agricultural Genomics,
BGI-Shenzhen, Shenzhen 518083, China
3Laboratory of Genomics and Molecular Biomedicine,
Department of Biology, University of Copenhagen, DK-2100 Copenhagen,
Denmark
4Key Laboratory of SFGA on Conservation Biology of
Rare Animals in the Giant Panda National Park (CCRCGP), Sichuan 611800,
China
5Key Laboratory of Wildlife Conservation, China State
Forestry Administration, Harbin 150040, China
6School of Life Sciences and Engineering, Foshan
University, Foshan, Guangdong Province, China
7School of Future Technology, University of Chinese
Academy of Sciences, Beijing 100049, China
8Guangdong Provincial Key Laboratory of Genome Read
and Write, BGI-Shenzhen, Shenzhen 518120, China
9China National GeneBank, BGI-Shenzhen, Shenzhen
518083, China.
10College of Life Sciences, Zhejiang University,
Hangzhou 310058, China
11MGI, BGI-Shenzhen, Shenzhen 518083, China
12BGI Education Center,University of Chinese Academy
of Sciences,Shenzhen 518083,China
13General Station for Surveillance of Wildlife
Diseases, National Forestry and Grassland Administration, Harbin 150040,
China
14Qingdao-Europe Advanced Institute for Life Sciences,
Qingdao 266555, China
15Foping National Nature Reserve, Hanzhong 723400,
China
†These authors contributed equally to this work.
*Corresponding authors: houzhijundz@163.com,
liuhuan@genomics.cn,
kk@bio.ku.dk and
liuquan1973@hotmail.com