Conclusions
Our findings did not demonstrate significant advantages of using CorMatrix during pediatric aortic valvuloplasty as compared to traditional pericardium. The biomaterial appears to be more susceptible to severe aortic regurgitation due to thickened, shortened, stiff, and retracted leaflets which caused lack of coaptation. Additional studies examining a larger patient population are warranted to further determine the long-term durability of repairs.
Limitations:
Our study has limitations inherent in all retrospective reviews. Specifically, we were limited by the small cohort size. Possible directions of future investigations should validate the durability of CorMatrix using a larger clinical experience of valve repairs.
Acknowledgments and Disclosure:
None.