2.3.5 Statistical analyses
SPSS version 24.0 was used to analyze the data. The results were showed
as mean (SD) and frequency (percent) for quantitative and qualitative
data, respectively. Intention to treat approach was used to include data
of subjects who discontinued the trial. The Kolmogorov– Smirnov test
was used to evaluate the distribution normality of data. Un-paired
sample student T-test and Chi-square test were applied to assess between
group differences of quantitative and qualitative data, respectively.
Analysis of covariance (ANCOVA) were applied to compare the quantitative
variables between groups post intervention. Also, paired sample student
T-test was used to compare the differences within groups between
baseline and post-intervention. Percent change was calculated as [100
Ă— (Intervention values -placebo values)/placebo values] to determine
the differences between groups. P <0.05 was considered
statistically significant.