What is known about this subject
- Doxorubicin is a life-saving chemotherapy regimen for breast cancer,
but it is associated with cardiomyopathy and congestive heart failure.
- In breast cancer patients, there are no routinely used, effective
interventions to prevent doxorubicin-induced cardiotoxicity.
- Coenzyme Q10 (CoQ10) is a fat-soluble antioxidant dietary supplement
which has been hypothesized to prevent cardiotoxicity from doxorubicin
and/or its metabolites.