Characteristics Data
Demographic data
Gender (male/female) 25 (6/19)
Age (years) 11±3
Weight (kg) 35.0±13.0
Body surface area (kg/m2) 1.15±0.28
Alanine aminotransferase (IU/L) 17±36
Aspartate aminotransferase (IU/L) 26±34
Alkaline phosphatase (IU/L) 174±120
Total bilirubin (μmol/L) 7.0±2.7
Uric acid (μmol/L) 420±143
Serum creatinine (μmol/L) 452±412
Cystatin C 4.21±3.28
Albumin (g/L) 39.3±5.7
White blood cell (109/L) 7.82±3.21
Hemoglobin (g/L) 115.3±21.9
Neutrophils (%) 60.6±15.2
IgG 7.25±3.57
CD3+ 81.67±68.96
CD4+ 37.48±9.77
CD19+ 12.68±14.61
Myeloperoxidase + 16 (64%)
Myeloperoxidase (RU/ml) 36.5±47.7
Pharmacokinetic data
C0h (ug/ml) 3.1±3.2
C0.33h (ug/ml) 6.2±6.7
C1h (ug/ml) 7.3±8.2
C3h (ug/ml) 4.3±3.6
AUC0-12h (mg/L·h) 45.11±30.26
Mycophenolate mofetil dosage (mg/d) 375 (125-1500)
Dosage forms (dispersible: capsule: Enteric-coated salt) 67:11:30
Concomitant prednisone (mg/d) 0: 0 ~10: >10
29:46:32