Animals
The male C57BL/6 mice (aged 6-8 weeks, weighing 20 ± 2g) mice we buy are
from the Vital River Laboratory Animal Technology Co. Ltd. (Beijing,
China). In order to adapt them to the new environment, the mice were
raised at least a week in the case of sufficient supply and free intake
and has a normal circadian rhythm before the experiment. All animal
tests were authorized by the Institutional Animal Care and Use Committee
of Qingdao University Health Science Center and were performed in
accordance with institutional and national guide-lines for the use and
care of animals for experiments.