Patient Selection and Data Collection
This retrospective study protocol was approved by the local ethics committee of Bakirkoy Dr. Sadi Konuk Training and Research Hospital, and the study was conducted according to the tenets of the Declaration of Helsinki. All subjects were informed about the study protocol, and their written consent was obtained (2021-258). Our retrospective study was composed of 290 patients who were enrolled from January 2017 to June 2019. All patients were admitted to the urology clinic of our hospital with the suspicion of PCa. The inclusion criteria were as follows: (i) having undergone 3-T mpMRI, (ii) having a single peripheral zone lesion with a PI-RADS v2 score of ≥3, and (iii) having a PSA value of >10 ng/mL and/or digital rectal examination positivity. The exclusion criteria were (i) absence of a 3-T mpMRI examination or the available mpMRI examination having non-diagnostic image quality, (ii) having any contraindication to MRI, and (iii) absence of fusion biopsy results. The patients included in the study and considered to be eligible for RP underwent robot-assisted laparoscopic radical prostatectomy (RALP) performed by two expert surgeons (S.Ş., A.İ.T.) using DaVinci Xi Surgical System ® (Intuitive Surgical, CA, USA). The clinical features of the patients, including age, PSA levels, PSA density (PSAD), prostate volume (PV), number of positive biopsy cores, the largest diameter of suspicious tumor lesions on diffusion-weighted MRI (DW-MRI), postoperative Gleason score, pathological stage, EPE, surgical margin (SM) positivity, SVI, and tumor volume were recorded.