Background:
Whether perioperative glycemic control or markers of inflammation is
associated with neurocognitive decline (NCD) after cardiac surgery was
examined.
Methods:Thirty patients undergoing cardiac surgery utilizing cardiopulmonary
bypass (CPB) were screened for NCD preoperatively and on post-operative
day four (POD4). Serum cytokine levels were measured and human
transcriptome analysis was performed on blood samples. Neurocognitive
data are presented as a change from baseline to POD4 in a score
standardized with respect to age and gender.