Results
Among 400 included patients, 2.8% had intervention-related ischemia
analogous to the type V MI definition. Receiver-operating
characteristics confirmed good discriminatory power for hs-cTnT and
creatine kinase myocardial band (CK-MB), with ischemia indicating
thresholds for hs-cTnT (1705.5 ng/l) and for CK-MB (113 U/l). The median
postoperative hs-cTnT/CK-MB increase differed significantly depending on
the type of surgery, with the highest increase after mitral valve and
the lowest after off-pump coronary surgery. Regression analysis
confirmed Maze procedure (p<0.001), cardiopulmonary bypass
time (p=0.03), emergency indications (p= 0.01) and blood transfusion
(p=0.02) as significant factors associated with hs-cTnT increase. In
contrast, CK-MB increase was also associated with mortality (p=0.002).
Intra-pericardial defibrillation was the only ischemia-independent
factor additionally associated with proposed thresholds
(p<0.001).