1 Introduction
Aplasia cutis congenita (ACC) is a rare congenital skin defect with an incidence of approximately 3/10,000, characterized by localized or extensive loss of epidermis, dermis, and occasionally subcutaneous tissue[1]. The exact etiology of ACC is unknown. The disease presents as isolated or multiple lesions that can appear anywhere on the body, but 70% to 90% of lesions are localized to the scalp’s vertex[1-3]. Most ACC tends to heal spontaneously, and its fatal complications include sagittal sinus hemorrhage, meningitis, and brain herniation. The treatment of ACC is controversial. Surgical treatment includes debridement and suturing, local flap transfer, free flap transfer, and skin grafting[2]. The risks include anesthesia-related complications, intraoperative bleeding, postoperative infection, and flap necrosis[4]. Conservative treatment mostly consists of regular dressing changes to promote spontaneous epithelialization, and its risks include bleeding, prolonged healing time, and wound infection[5].