1 Introduction
Aplasia cutis congenita (ACC) is a rare congenital skin defect with an
incidence of approximately 3/10,000, characterized by localized or
extensive loss of epidermis, dermis, and occasionally subcutaneous
tissue[1]. The exact etiology of ACC is unknown.
The disease presents as isolated or multiple lesions that can appear
anywhere on the body, but 70% to 90% of lesions are localized to the
scalp’s vertex[1-3]. Most ACC tends to heal
spontaneously, and its fatal complications include sagittal sinus
hemorrhage, meningitis, and brain herniation. The treatment of ACC is
controversial. Surgical treatment includes debridement and suturing,
local flap transfer, free flap transfer, and skin
grafting[2]. The risks include anesthesia-related
complications, intraoperative bleeding, postoperative infection, and
flap necrosis[4]. Conservative treatment mostly
consists of regular dressing changes to promote spontaneous
epithelialization, and its risks include bleeding, prolonged healing
time, and wound infection[5].