Meta-regression: Relation of change in serum potassium after diuretic to change in aldosterone
Random-effects meta-regression was also used to examine whether change in PA was associated with serum potassium and we found there was no relationship (coefficient -0.09, 95% CI -0.30, 0.12, P = 0.402, Figure 4A) with similar findings in studies where studies were the participants were previously untreated/washout (coefficient -0.13, 95% CI -0.31, 0.06, P = 0.174, Figure 4B).