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\begin{document}

\title{Is inmunotherapy effective on the treatment of secretory azoospermia ?}



\author[1]{bo song}%
\author[2]{mei sun}%
\author[2]{weiping qian}%
\affil[1]{shenzhen Hospital }%
\affil[2]{Affiliation not available}%


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  \date{May 20, 2024}


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\begin{abstract}
Aims of the study To assess the effectiveness of medicine and
immunotherapy on secretory azoospermia. Methods used to conduct the
study The husband with azoospermia was 63 years old and his 35-year-old
wife presented secondary infertility for 5 years. The male had operation
and chemotherapy of stomach cancer five years ago. After operation and
chemotherapy,the male made the treatment on immunotherapy until today.
In this treatment, andriol and aescuven forte was given. The total
treatment were fourteen months. Semen, blood hormone and pregnancy were
detected. Results of the study Six months after treatment, sperm
appeared in the semen(2018-12-13:sperm concentration 3\selectlanguage{ngerman}×106/ml\selectlanguage{english},PR
0\%\selectlanguage{english}), ICSI was made while ET was failure. 1 year later, the semen was
changed greatly (2019-01-29\selectlanguage{english}:sperm concentration 43x106/ml\selectlanguage{english},PR
15\%\selectlanguage{english},acrosin 43.1\selectlanguage{greek}μ\selectlanguage{english}IU/106), second ICSI was made and TET was failed. In
May,2020, third cycle ICSI was made,frozen embryo was transplanted in
December and in March the wife was conceived for morn than four months.
Conclusions We have discussed and published the medicine treatment of
azoospermia in 2017 while it is the first time to find the relationship
between the spermatogenesis and immunotherapy. Form this case, it could
been concluded that Aescuven Forte with Testosterone Undecanoate is good
for the patient with testicle dysfunction whhile the time of medicine
treatment is better for more than six months. Immunotherapy might be
good for spermatogenesis. FSH is a good for ample in the treatment on
azoospermia.%
\end{abstract}%



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