Funnel plot of comparison: 1 HFpEF in OSA vs non OSA, outcome: 1.1 LVEF.
Figure 3: Relationship between OSA and Echocardiographic parameters.
(In a separate word file)
Figure 4: Relationship between OSA severity and Echocardiographic parameters.
References:
1. Dunlay SM, Roger VL, Redfield MM. Epidemiology of heart failure with preserved ejection fraction. Nat Rev Cardiol. 2017;14(10):591-602.
2. Paulus WJ, Tschope C. A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation. J Am Coll Cardiol. 2013;62(4):263-71.
3. Khattak HK, Hayat F, Pamboukian SV, Hahn HS, Schwartz BP, Stein PK. Obstructive Sleep Apnea in Heart Failure: Review of Prevalence, Treatment with Continuous Positive Airway Pressure, and Prognosis. Tex Heart Inst J. 2018;45(3):151-61.
4. Gonzaga C, Bertolami A, Bertolami M, Amodeo C, Calhoun D. Obstructive sleep apnea, hypertension and cardiovascular diseases. J Hum Hypertens. 2015;29(12):705-12.
5. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gotzsche PC, Ioannidis JP, et al. The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. Bmj. 2009;339:b2700.
6. Nagueh SF, Smiseth OA, Appleton CP, Byrd BF, 3rd, Dokainish H, Edvardsen T, et al. Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. Eur Heart J Cardiovasc Imaging. 2016;17(12):1321-60.
7. Kapur VK, Auckley DH, Chowdhuri S, Kuhlmann DC, Mehra R, Ramar K, et al. Clinical Practice Guideline for Diagnostic Testing for Adult Obstructive Sleep Apnea: An American Academy of Sleep Medicine Clinical Practice Guideline. J Clin Sleep Med. 2017;13(3):479-504.
8. Altekin RE, Yanikoglu A, Baktir AO, Karakas MS, Ozel D, Cilli A, et al. Assessment of subclinical left ventricular dysfunction in obstructive sleep apnea patients with speckle tracking echocardiography. Int J Cardiovasc Imaging. 2012;28(8):1917-30.
9. Altiparmak IH, Erkus ME, Polat M, Yalcin F, Sak ZH, Sezen H, et al. Relation of elastic properties of pulmonary artery with left ventricular abnormalities and aortic stiffness in patients with moderate to severe obstructive sleep apnea: A cross-sectional echocardiographic study. Turk Kardiyol Dern Ars. 2016;44(4):289-99.
10. Arias Miguel A, García-Río F, Alonso-Fernández A, Mediano O, Martínez I, Villamor J. Obstructive Sleep Apnea Syndrome Affects Left Ventricular Diastolic Function. Circulation. 2005;112(3):375-83.
11. Arikawa T, Toyoda S, Haruyama A, Amano H, Inami S, Otani N, et al. Impact of Obstructive Sleep Apnoea on Heart Failure with Preserved Ejection Fraction. Heart, Lung and Circulation. 2016;25(5):435-41.
12. Butt M, Dwivedi G, Shantsila A, Khair Omer A, Lip Gregory YH. Left Ventricular Systolic and Diastolic Function in Obstructive Sleep Apnea. Circulation: Heart Failure. 2012;5(2):226-33.
13. Cicek D, Lakadamyali H, Yagbasan BD, Sapmaz I, Muderrisoglu H. Obstructive sleep apnoea and its association with left ventricular function and aortic root parameters in newly diagnosed, untreated patients: a prospective study. J Int Med Res. 2011;39(6):2228-38.
14. Danica LP, Krotin M, Zdravkovic M, Soldatovic I, Zdravkovic D, Brajkovic M, et al. Early left ventricular systolic and diastolic dysfunction in patients with newly diagnosed obstructive sleep apnoea and normal left ventricular ejection fraction. ScientificWorldJournal. 2014;2014:898746.
15. Glantz H, Thunstrom E, Johansson MC, Wallentin Guron C, Uzel H, Ejdeback J, et al. Obstructive sleep apnea is independently associated with worse diastolic function in coronary artery disease. Sleep Med. 2015;16(1):160-7.
16. Haruki N, Takeuchi M, Nakai H, Kanazawa Y, Tsubota N, Shintome R, et al.
17. Kawanishi Y, Ito T, Okuda N, Emura N, Hayashi T, Futai R, et al. Alteration of myocardial characteristics and function in patients with obstructive sleep apnea. Int J Cardiol. 2009;133(1):129-31.
18. Kim SH, Cho GY, Shin C, Lim HE, Kim YH, Song WH, et al. Impact of obstructive sleep apnea on left ventricular diastolic function. Am J Cardiol. 2008;101(11):1663-8.
19. Koga S, Ikeda S, Urata J, Kohno S. Effect of nasal continuous positive airway pressure in men on global left ventricular myocardial performance in patients with obstructive sleep apnea syndrome. Am J Cardiol. 2008;101(12):1796-800.
20. Lisi E, Faini A, Bilo G, Lonati LM, Revera M, Salerno S, et al. Diastolic dysfunction in controlled hypertensive patients with mild-moderate obstructive sleep apnea. Int J Cardiol. 2015;187:686-92.
21. Romero-Corral A, Somers VK, Pellikka PA, Olson EJ, Bailey KR, Korinek J, et al. Decreased right and left ventricular myocardial performance in obstructive sleep apnea. Chest. 2007;132(6):1863-70.
22. Wachter R, Luthje L, Klemmstein D, Luers C, Stahrenberg R, Edelmann F, et al. Impact of obstructive sleep apnoea on diastolic function. Eur Respir J. 2013;41(2):376-83.
23. Yang SQ, Han LL, Dong XL, Wang CY, Xia H, Liu P, et al. Mal-effects of obstructive sleep apnea on the heart. Sleep Breath. 2012;16(3):717-22.
24. Kane GC, Karon BL, Mahoney DW, Redfield MM, Roger VL, Burnett JC, Jr., et al. Progression of left ventricular diastolic dysfunction and risk of heart failure. JAMA. 2011;306(8):856-63.
25. Redfield MM, Jacobsen SJ, Burnett JC, Jr., Mahoney DW, Bailey KR, Rodeheffer RJ. Burden of systolic and diastolic ventricular dysfunction in the community: appreciating the scope of the heart failure epidemic. JAMA. 2003;289(2):194-202.