Endothelialization
CCTA performed at 6 months post procedure showed that the average linear attenuation coefficient of LAA was less than 100 Hu in 44 cases (52.4%), suggesting complete device endothelialization. In 7 cases (8.3%) the average linear attenuation coefficient of LAA was more than 100 Hu in the absence of visible PDL, suggesting incomplete device endothelialization. Status of device endothelialization could not be determined in those patients with PDL by CCTA (n=33).
Age, sex, BMI, presence of hypertension/diabetes, AF pattern, preoperative troponin, NT-ProBNP, fibrinogen, D-dimer, LVEF, maximum diameter of LAA orifice, LAV, LAAV or device size did not differ between complete and incomplete endothelialization groups. Univariate logistic regression analysis showed that all the clinical factors above were not statistically significant and could not predict the degree of device endothelialization after procedure.