Conclusion
We identified tree pollen allergy, nocturnal cough, wheezing, a FEF75 < 65% and a younger age as significant predictors of AHR. Combining these predictors in a weighted multivariate score improved the diagnostic value. This novel score might be used in children suspected of having asthma, but without an obstructive pattern, to identify those who probably will show a positive response to the MCC as well as to substantiate the result of the MCC. Further prospective studies may help to demonstrate the predictive value of this score.