Limitations
The comparability of our study population recruited from a specialized
tertiary center for pediatric allergy is limited. We included only
children with asthma-like symptoms and without obstructive patterns. We
also excluded patients with exercise-related leading symptoms. Due to
these exclusion criteria, only patients with certain conditions could be
recruited onto the study. However, our findings are extracted from a
real-life setting and it represents the routine diagnostic procedures.
The large sample size is another strength of our study.