Abstract
Noonan syndrome is a genetic multisystem disorder characterized by
distinctive facial features, developmental delay, congenital heart
disease, and other conditions. It is associated with mutation of genes
encoding the proteins in the RAS-MAPK pathway, including PTPN11. We
herein describe the first case of Noonan syndrome complicated with
hepatocellular carcinoma.
Key words : Noonan syndrome, hepatocellular carcinoma, PTPN11.