Mutation Stability: ΔΔG: (kcal/mol) Flexibility: ΔΔSVib ENCoM (kcal.mol-1K-1)
A2V -0.015 (Destabilizing) 0.129 (Increase of molecule flexibility)
A2S -0.091 (Destabilizing) 0.080 (Increase of molecule flexibility)
D3G -0.975 (Destabilizing) 0.464 (Increase of molecule flexibility)
L17I 0.468 (Stabilizing) -0.022 (Decrease of molecule flexibility)
H125S -1.279 (Destabilizing) 0.582 (Increase of molecule flexibility)
T175M 2.248 (Stabilizing) -0.780 (Decrease of molecule flexibility)
D209Y 1.702 (Stabilizing) -0.674 (Decrease of molecule flexibility)