1 INTRODUCTION
Invasive pulmonary aspergillosis
(IPA) has been traditionally described as the leading cause of invasive
fungal disease in immunocompromised patients with hematologic
malignancies associated with neutropenia and also those with solid organ
transplantation, neoplasm, and human immunodeficiency virus (AIDS)
[1,2]. Recently, the profile of patients at high risk for IPA has
expanded to include those with end-stage chronic obstructive pulmonary
disease (COPD) requiring corticosteroid therapy, severe cirrhosis, and
those receiving immunosuppressive therapies (i.e., monoclonal agents)
[3]. However, to the best of our knowledge, there have been no
reports of IPA associated with hepatocellular carcinoma. We report a
case of recurrent hepatocellular carcinoma in which IPA developed after
the start of corticosteroid therapy.