Patient characteristics
There were 112 patients accepted thalidomide treatment in Department of Pediatrics, Sun Yat-sen Memorial Hospital between March 2018 and December 2019.There were 19 patientswho did not have transfusion volume record before and during thalidomide treatment, while 10 patients did not have the first month visit, and 6 patients did not have the third month visit. Finally, 35 patients were excluded from efficacy and safety analysis for thalidomide. The 77 included patients’ clinical characteristics were illustrated inTable 1 .