Fig. 2. The fabricated
device showing a fish loaded in trap A and simulation overlays of the
electric voltage, pressure drop and shear stress for traps B, C, and D
respectively. The wire for electric stimulation running through the
indirect flow channel is highlighted in red
In all experiments with zebrafish larvae presented in the following
sections, the control groups with no off-chip chemical exposure and no
on-chip electric stimulation demonstrated no movement in the device with
zero RD and zero TBF. The responses observed in the test groups was
therefore associated with the effect of electric stimulation and the
assayed chemicals in Table 1 (Supplementary video2).