Fig. 5. Effect of DMSO,
haloperidol and quinpirole on 6 dpf zebrafish larvae’s electric
response. (A) Exposure timeline for zebrafish larvae. Electric-induced
(B) RD and (C) TBF of zebrafish larvae exposed to no chemical (control),
16.7 μM quinpirole, DMSO (0.4%), 16.7 μM haloperidol and quinpirole
after exposure to 16.7 μM haloperidol. Lines within the box mark the
median data points. Upper and lower box boundaries are the
75th and the 25th percentiles,
respectively. Whiskers are the highest and lowest data points obtained.
*: P<0.05, **: P<0.01, ***: P<0.001. n=15
larvae per experimental condition in three independent trials, for a
total of N = 45 larvae tested per group.