Ragweed pollen allergy
Ragweed allergy dominates weed pollen allergy in North America and,
after the accidental introduction of ragweed in Europe about one hundred
years ago, is in continuous progression in the continent.
Major allergen Amb a 1, a pectate lyase, is a true marker of ragweed
allergy and presents low cross-reactivity with related proteins from
other pollen sources58. However, there is
an extensive cross-reactivity among different Ambrosia species59. Currently, there
are AIT products extensively documented in adults60 both in American and
European patients as well as in children61 and these products
are available worldwide for AIT practice.