SOURCE Allergen Sensitization rate Available for routine CRD Significance
POLLEN Grasses Phl p 1 >90% S,M Expansin. Present in different plant parts. Major allergen and usually initiates sensitization
Phl p 5 >60% S,M Unknown function. Most abundant pollen protein
Phl p 7 <10% S,M Pan-allergen in pollens. Calcium -binding
Phl p 12 5-50% S,M Pan-allergen (food/pollen ). Structural protein
Birch
Bet v 1
>90%
S,M
Pan-allergen (food/pollen) Regulatory protein. Highly expressed in case of biotic stress.
Olive tree Ole e 1 >90% S,M Unknown function
Olive Ole e 7 0-50% S,M nsLTP, minor allergen. Disease severity marker
Olive Ole e 9 0-50% S,M Glucanase, minor allergen. Highly vairable in different olive cultivars
Russian thistle Sal k 1 >90% S,M Pectin methylesterase
Plain tree Pla a 1 >90 S,M Invertase inhibitor
Arizona cedar Cup a 1 >90% S,M Pectate lyase. Homologous and cross-reactive to Cry j 1 from Japanesse cedar and Jun a 1 from mountain cedar
English plantain Pla l 1 >70 S,M Ole e 1 like. Non-cross reactive
Artemisia Art v 1 >70 S,M Defensin like
Ragweed Amb a 1 Pectate lyase
Parietaria Parj 2 >90% S,M ns LTP
FOODS Peach Pru p 3 S,M ns LTP. Very stable. Frequent initiator in LTP syndrome
Peanut Ara h 1 11S Albumin. Storage protein. Highly abundant
Ara h 2 2S albumin. Storage protein. >Highly abundant. Risk marker for severe reactions
Ara h 3 11S Albumin. Storage protein. Highly abundant
Ara h 5 Profilin
Ara h 8 PR10. Bet v 1 like
Ara h 9 nsLTP (Pru p 3 related)
MITES Dermatophagoides pteronyssinus Der p 1 >90% S,M Cystein protease. Associated to mite fecal particles
Der p 2 >90% S,M NCP2. Lipid binding protein. MD2 link. Associated to mite bodies
Der p 10 <10% S,M Pan-allergen in arthropods.
Der p 23 Peritrophin-like protein
Lepidoglyphus destructor Lep d 2 >90% M Related to Der p 2, but without IgE cross-reactivity. Cross-reactive with Group 2 proteins from other minor/storage mites.
EPITHELIA Cat Fel d 1 >90% S,M Secretoglobulin.
Fel d 4,7 <50% S,M Lipocalins. Cross-reactivity with Can f 1
Dog Can f 1 >50% S,M Lipocalin
Can f 5 >50% S,M Kalikrein. Serin protease. Regulating semen liquefaction. Present in male dogs