Dynamic changes in MPG:
MG significantly increased after the MitraClip procedure (1.5±1.1 mmHg to 3.5±1.7 mmHg, p=0.03) in the overall cohort. Elevated MG values above 4.5 mmHg were measured intraprocedurally in 21 patients (12%) –group 2 .
Concerning MG’s peri-interventional dynamics, we found a decrease in MG to values below 4.5 mmHg in 11 patients (52%) from group 2 at discharge – group 2B . In total, 94% of patients (n=165) presented with an MG <4.5 mmHg and only 6% of patients (n=10) had persistent increased MG ≥4.5 mmHg at discharge – group 2A .
At six-months FU, the following MG values were documented: (i) increase to values above 4.5 mmHg in nine patients (5.45%) from group 1 and (ii) decrease to values below 4.5 mmHg in two patients (20 %) from group 2A, in addition to 11 patients with a pre-discharge reduction in MG. Overall, we found 146 patients (91%) with MG <4.5 mmHg and 14 patients (9%) with MG ≥4.5 mmHg at six-month FU. The dynamics of MG values over time are presented in Figure 1.