DECLARATION OF INTERESTS
No potential competing interest was reported by the author.
REFERENCES
1. Hui DS. Epidemic and Emerging Coronaviruses (Severe Acute respiratory Syndromeand Middle East respiratory Syndrome). Clin Chest Med. 2017 Mar;38 (1) :71 - 86. doi:10.1016/j.ccm.2016.11.007. Epub 2016 Dec 16. PMID: 28159163; PMCID: PMC7131795.
2. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, Zhao X, Huang B, Shi W, Lu r, NiuP, Zhan F, Ma X, Wang D, Xu W, Wu G, Gao GF, Tan W; China Novel Coronavirus Investigating and research Team. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med. 2020 Feb 20;382 (8) :727 - 733. doi:10.1056/NEJ Moa2001017. Epub 2020 Jan 24. PMID: 31978945; PMCID: PMC7092803.
3. Paraskevis D, Kostaki EG, Magiorkinis G, Panayiotakopoulos G, Sourvinos G, Tsiodras S. Full - genome evolutionary analysis of the novel corona virus (2019 - nCoV) rejects the hypothesis of emergence as a result of a recent recombination event. InfectGenet Evol. 2020 Apr;79:104212. doi: 10.1016/j.meegid. 2020.104212. Epub 2020 Jan29. PMID: 32004758; PMCID: PMC7106301.
4. Lu r, Zhao X, Li J, Niu P, Yang B, Wu H, Wang W, Song H, Huang B, Zhu N, Bi Y, Ma X, Zhan F, Wang L, Hu T, Zhou H, Hu Z, Zhou W, Zhao L, Chen J, Meng Y, Wang J, Lin Y, Yuan J, Xie Z, Ma J, Liu WJ, Wang D, Xu W, Holmes EC, Gao GF, Wu G, Chen W, Shi W, Tan W. Genomic characterisation andepidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet.2020 Feb 22;395 (10224) :565 - 574. doi: 10.1016/S0140 - 6736 (20) 30251 - 8. Epub 2020 Jan 30.PMID: 32007145; PMCID: PMC7159086.
5. Mueller S. On DNA Signatures, Their Dual - Use Potential for GMO Counterfeiting, and aCyber - Based Security Solution. Front Bioeng Biotechnol. 2019 Aug 7;7:189. doi:10.3389/fbioe.2019.00189. PMID: 31440503; PMCID: PMC6693310.
6. Ziebuhr J. Molecular biology of severe acute respiratory syndrome coronavirus. CurrOpin Microbiol. 2004 Aug;7 (4) :412 - 9. doi: 10.1016/j.mib.2004.06.007. PMID: 15358261;PMCID: PMC7108451.
7. Susan r. Weiss, Julian L. Leibowitz, Chapter 4 - Coronavirus Pathogenesis, Editor (s) :Karl Maramorosch, Aaron J. Shatkin, Frederick A. Murphy, Advances in Virus research, Academic Press, Volume 81, 2011, Pages 85 - 164, ISSN 0065 - 3527, ISBN 9780123858856, https://doi.org/10.1016/B978 - 0 - 12 - 385885 - 6.00009 - 2.
8. Brian DA, Baric rS. Coronavirus genome structure and replication. Curr Top Microbiol Immunol. 2005;287:1 - 30. doi: 10.1007/3 - 540 - 26765 - 4_1. PMID: 15609507;PMCID: PMC7120446.
9. Mohammed MEA. The percentages of SARS - CoV - 2 protein similarity and identity with SARS - CoVand BatCoV raTG13 proteins can be used as indicators of virus origin. J Proteins Proteom. 2021 Apr 9:1 - 11. doi: 10.1007/s42485 - 021 - 00060 - 3. Epub ahead of print. PMID: 33850392; PMCID: PMC8033097.
10. Zolfaghari Emameh, r., Eftekhari, M., Nosrati, H. et al. Identification and characterization of a silent mutation in rNA binding domain of N protein coding gene fromSARS - CoV - 2. BMC res Notes 14, 10 (2021). https://doi.org/10.1186/s13104 - 020 - 05439 - x
11. Neuman BW, Kiss G, Kunding AH, Bhella D, Baksh MF, Connelly S, Droese B, KlausJP, Makino S, Sawicki SG, Siddell SG, Stamou DG, Wilson IA, Kuhn P, Buchmeier MJ. Astructural analysis of M protein in coronavirus assembly and morphology. J Struct Biol.2011 Apr;174 (1) :11 - 22. doi: 10.1016/j.jsb.2010.11.021. Epub 2010 Dec 3. PMID:21130884; PMCID: PMC4486061.
12. Siu KL, Chan CP, Kok KH, Chiu - Yat Woo P, Jin DY. Suppression of innate antiviral response bysevere acute respiratory syndrome coronavirus M protein is mediated through the firsttransmembrane domain. Cell Mol Immunol. 2014 Mar;11 (2) :141 - 9. doi: 10.1038/cmi.2013.61. Epub2014 Feb 10. PMID: 24509444; PMCID: PMC4003381.
13. Schoeman D, Fielding BC. Coronavirus envelope protein: current knowledge. Virol J. 2019May 27;16 (1) :69. doi: 10.1186/s12985 - 019 - 1182 - 0. PMID: 31133031; PMCID: PMC6537279.
14. Al - Tawfiq JA, Al - Homoud AH, Memish ZA. remdesivir as a possible therapeutic optionfor the COVID - 19. Travel Med Infect Dis. 2020 Mar - Apr;34:101615. doi:10.1016/j.tmaid.2020.101615. Epub 2020 Mar 5. PMID: 32145386; PMCID: PMC7129391.
15. Agostini ML, Andres EL, Sims AC, Graham rL, Sheahan TP, Lu X, Smith EC, Case JB, FengJY, Jordan r, ray AS, Cihlar T, Siegel D, Mackman rL, Clarke MO, Baric rS, Denison Mr.Coronavirus Susceptibility to the Antiviral remdesivir (GS - 5734) Is Mediated by the ViralPolymerase and the Proofreading Exoribonuclease. mBio. 2018 Mar 6;9 (2) :e00221 - 18. doi:10.1128/mBio.00221 - 18. PMID: 29511076; PMCID: PMC5844999.
16. de Wit E, Feldmann F, Cronin J, Jordan r, Okumura A, Thomas T, Scott D, Cihlar T, Feldmann H. Prophylactic and therapeutic remdesivir (GS - 5734) treatment in the rhesus macaquemodel of MErS - CoV infection. Proc Natl Acad Sci U S A. 2020 Mar 24;117 (12) :6771 - 6776. doi:10.1073/pnas.1922083117. Epub 2020 Feb 13. PMID: 32054787; PMCID: PMC7104368.
17. Pilon AC, Valli M, Dametto AC, Pinto MEF, Freire rT, Castro - Gamboa I, Andricopulo AD, Bolzani VS. NuBBEDB: an updated database to uncover chemical and biological information fromBrazilian biodiversity. Sci rep. 2017 Aug 3;7 (1) :7215. doi: 10.1038/s41598 - 017 - 07451 - x. PMID:28775335; PMCID: PMC5543130.
18. Khot WY, Nadkar MY. The 2019 Novel Coronavirus Outbreak - A Global Threat. J AssocPhysicians India. 2020 Mar;68 (3) :67 - 71. PMID: 32138488.
19. Zeng YM, Xu XL, He XQ, Tang SQ, Li Y, Huang YQ, Harypursat V, Chen YK. Comparativeeffectiveness and safety of ribavirin plus interferon - alpha, lopinavir/ritonavir plus interferon - alpha, and ribavirin plus lopinavir/ritonavir plus interferon - alpha in patients with mild to moderate novelcoronavirus disease 2019: study protocol. Chin Med J (Engl). 2020 May 5;133 (9) :1132 - 1134. doi:10.1097/CM9.0000000000000790. PMID: 32149772; PMCID: PMC7213617.
20. McGraw PN, Menzinger M, Muñuzuri AP. Harmonic resonant excitation of flow - distributedoscillation waves and Turing patterns driven at a growing boundary. Phys rev E Stat Nonlin SoftMatter Phys. 2009 Aug; 80 (2 Pt 2) :026209. doi: 10.1103/PhysrevE. 80.026209. Epub 2009 Aug20. PMID: 19792233.
21. Martinez MA. Compounds with Therapeutic Potential against Novel respiratory 2019Coronavirus. Antimicrob Agents Chemother. 2020 Apr 21;64 (5) :e00399 - 20. doi:10.1128/AAC.00399 - 20. PMID: 32152082; PMCID: PMC7179632.
22. Gordon CJ, Tchesnokov EP, Feng JY, Porter DP, Götte M. The antiviral compound remdesivirpotently inhibits rNA - dependent rNA polymerase from Middle East respiratory syndromecoronavirus. J Biol Chem. 2020 Apr 10;295 (15) :4773 - 4779. doi: 10.1074/jbc.AC120.013056. Epub2020 Feb 24. PMID: 32094225; PMCID: PMC7152756.
23. Sheahan TP, Sims AC, Leist Sr, Schäfer A, Won J, Brown AJ, Montgomery SA, Hogg A, Babusis D, Clarke MO, Spahn JE, Bauer L, Sellers S, Porter D, Feng JY, Cihlar T, Jordan r, DenisonMr, Baric rS. Comparative therapeutic efficacy of remdesivir and combination lopinavir, ritonavir, and interferon beta against MErS - CoV. Nat Commun. 2020 Jan 10;11 (1) :222. doi:10.1038/s41467 - 019 - 13940 - 6. PMID: 31924756; PMCID: PMC6954302.
24. Trott O, Olson AJ. AutoDock Vina: improving the speed and accuracy of docking with a newscoring function, efficient optimization, and multithreading. J Comput Chem. 2010 Jan30;31 (2) :455 - 61. doi: 10.1002/jcc.21334. PMID: 19499576; PMCID: PMC3041641.
25. Van Meter, r., Satoh, T., Ladd, T.D. et al. Path selection for quantum repeater networks.Netw.Sci. 3, 82–95 (2013). https://doi.org/10.1007/s13119 - 013 - 0026 - 2
26. Xin T, Che L, Xi C, Singh A, Nie X, Li J, Dong Y, Lu D. Experimental Quantum PrincipalComponent Analysis via Parametrized Quantum Circuits. Phys rev Lett. 2021 Mar19;126 (11) :110502. doi: 10.1103/PhysrevLett.126.110502. PMID: 33798351.
27. Henriques AG. What Chern - Simons theory assigns to a point. Proc Natl Acad Sci U S A.2017 Dec 19;114 (51) :13418 - 13423. doi: 10.1073/pnas.1711591114. Epub 2017 Dec 5. PMID:29208715; PMCID:PMC5754777.
28. Honda M. Supersymmetric Solutions and Borel Singularities for N == == 2 Supersymmetric Chern - SimonsTheories. Phys rev Lett. 2018 Jul 13; 121 (2) :021601. doi:10.1103/PhysrevLett.121.021601. PMID:30085688.
29. Simón J. Brane Effective Actions, Kappa - Symmetry and Applications. Living rev relativ. 2012; 15 (1) :3. doi: 10.12942/lrr - 2012 - 3. Epub 2012 Feb 27. PMID: 28179834; PMCID: PMC5256004.
30. Cavaglià A, Fioravanti D, Gromov N, Tateo r. Quantum spectral curve of the N = 6 supersymmetric Chern - Simons theory. Phys rev Lett. 2014 Jul 11; 113 (2) :021601.doi:10.1103/PhysrevLett.113.021601. Epub 2014 Jul 11. PMID: 25062163.
31. Mabkhot YN, Alatibi F, El - Sayed NN, Al - Showiman S, Kheder NA, Wadood A, rauf A, Bawazeer S, HaddaTB. Antimicrobial Activity of Some Novel Armed Thiophene Derivatives andPetra/Osiris/Molinspiration (POM) Analyses. Molecules. 2016 Feb 17; 21 (2) :222.doi:10.3390/molecules21020222. PMID: 26901173; PMCID: PMC6273311.
32. Khan T, Lawrence AJ, Azad I, raza S, Joshi S, Khan Ar. Computational Drug Designing and Predictionof Important Parameters Using in silico Methods - A review. Curr Comput Aided Drug Des. 2019; 15 (5) :384 - 397. doi: 10.2174/1573399815666190326120006. PMID: 30914032.
33. Ulrich H, Pillat MM. CD147 as a Target for COVID - 19 Treatment: Suggested Effects of Azithromycin andStem Cell Engagement. Stem Cell rev rep. 2020 Jun;16 (3) :434 - 440. doi: 10.1007/s12015 - 020 - 09976 - 7. PMID: 32307653; PMCID: PMC7167302.
34. Chan JF, Kok KH, Zhu Z, Chu H, To KK, Yuan S, Yuen KY. Genomic characterization of the 2019 novelhuman - pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan.Emerg Microbes Infect. 2020 Jan 28;9 (1) :221 - 236. doi: 10.1080/22221751.2020.1719902. Erratumin: Emerg Microbes Infect. 2020 Dec;9 (1) :540. PMID: 31987001; PMCID: PMC7067204.
35. Kong r, Yang G, Xue r, Liu M, Wang F, Hu J, Guo X, Chang S. COVID - 19 Docking Server: a meta serverfor docking small molecules, peptides and antibodies against potential targets of COVID - 19.Bioinformatics. 2020 Dec 22;36 (20) :5109 - 5111. doi: 10.1093/bioinformatics/btaa645. PMID:32692801; PMCID: PMC7558834.
36. Shi Y, Zhang X, Mu K, Peng C, Zhu Z, Wang X, Yang Y, Xu Z, Zhu W. D3Targets - 2019 - nCoV: a webserver for predicting drug targets and for multi - target and multi - site based virtual screening against COVID - 19. Acta Pharm Sin B. 2020 Jul;10 (7) :1239 - 1248. doi: 10.1016/j.apsb.2020.04.006. Epub 2020 Apr 20.PMID: 32318328; PMCID: PMC7169934.
37. Camila Silva de Magalhães, Diogo Marinho Almeida, Helio José Correa Barbosa, Laurent EmmanuelDardenne, A dynamic niching genetic algorithm strategy for docking highly flexible ligands.Information Sciences, Volume 289, 2014, Pages 206 - 224, ISSN 0020 - 0255, https://doi.org/10.1016/j.ins.2014.08.002.
38. van Loock P, Ladd TD, Sanaka K, Yamaguchi F, Nemoto K, Munro WJ, Yamamoto Y. Hybrid quantumrepeater using bright coherent light. Phys rev Lett. 2006 Jun 23;96 (24) :240501. doi:10.1103/PhysrevLett.96.240501. Epub 2006 Jun 19. PMID: 16907223.
39. Zhao B, Chen ZB, Chen YA, Schmiedmayer J, Pan JW. robust creation of entanglement between remote memory qubits. Phys rev Lett. 2007 Jun 15;98 (24) :240502. doi:10.1103/PhysrevLett.98.240502. Epub 2007 Jun 15. PMID: 17677950.
40. Santos KB, Guedes IA, Karl ALM, Dardenne LE. Highly Flexible LigandDocking: Benchmarking of the DockThor Program on the LEADS - PEP Protein - Peptide Data Set. J Chem Inf Model. 2020 Feb 24;60 (2) :667 - 683. doi:10.1021/acs.jcim.9b00905. Epub 2020 Jan 27. PMID: 31922754.
41. Iheagwam FN, rotimi SO. Computer - Aided Analysis of Multiple SARS - CoV - 2 Therapeutic Targets: Identification of Potent Molecules from AfricanMedicinal Plants. Scientifica (Cairo). 2020 Sep 12;2020:1878410. doi:10.1155/2020/1878410. PMID: 32963884; PMCID: PMC7492903.
42. Müller S. Flexible heuristic algorithm for automatic molecule fragmentation: application to the UNIFAC group contribution model. J Cheminform. 2019; 11:57.Published 2019 Aug 20.doi:10.1186/s13321 - 019 - 0382 - 3
43. Shi J, Chen S, Lu Y, et al. An Approach to Cryptography Based on Continuous - Variable Quantum Neural Network. Sci rep. 2020;10 (1) :2107. Published 2020 Feb 7. doi:10.1038/s41598 - 020 - 58928 - 1
44. Nalewajski, r.F. Quantum information descriptors and communications in molecules. JMath Chem 52, 1292–1323 (2014). https://doi.org/10.1007/s10910 - 014 - 0311 - 7
45. Giribet, Gaston & Merino, Nelson & Miskovic, Olivera & Zanelli, Jorge. (2014). Black hole solutions in Chern - Simons AdS supergravity. Journal of High Energy Physics. 2014. 10.1007/JHEP08 (2014) 083.
46. Baianu, Ion & Glazebrook, James & Brown, ronald. (2009). Algebraic Topology Foundations of Supersymmetry and Symmetry Breaking in Quantum Field Theory and Quantum Gravity: A review. Symmetry, Integrability and Geometry: Methods and Applications. 5. 10.3842/SIGMA.2009.051.
47. Horvathy, Peter. (1999). Topology of non - topological Chern - Simons vortices.
48. Bañados, Máximo & Troncoso, ricardo & Zanelli, Jorge. (1996). Higher dimensional Chern - Simons supergravity. Physical review D. 54. 10.1103/PhysrevD.54.2605.
49. Bañados, Máximo & Gomberoff, Andres. (1996). Black Hole Entropy in the Chern - Simons Formulation of 2+1 Gravity.