3.3. The relative levels of allergen-specific IgD but not IgG4
depend on the status of egg allergy
The relative levels of OVM-specific IgD were lower than those of
OVA-specific IgD in the CAE groups (Fig 2A). In contrast, the relative
levels of OVM-specific IgD were similar to levels of OVM-specific IgD in
the PAE and OGE groups (Fig 2B and 2C). The relative levels of
OVM-specific IgG4 and OVA-specific IgG4 did not differ between the
groups (Fig. 2E-H). Therefore, the ratio of OVM-specific IgD to
OVA-specific IgD increase as children outgrow egg allergy, whereas the
ratio of OVM-specific IgG4 to OVA-specific IgG4 did not change (Fig 2I
and 2J).